General advances in the field of Human Embryonic Stem Cells
Transcriptome characterization elucidates signaling networks that control human ES growth and differentiation. R. Brandenberger, H. Wei, S. Zhang, S. Lei, J, Murage, G. Fisk, Y. Li, C. Xu, R. Fang, K. Guegler, M. Rao, R. Mandalam, J. Lebkowski, L. Stanton. Nature Biotechnology 2004; 22: 707-716.

Basic Fibroblast Growth Factor Supports Undifferentiated Human Embryonic Stem Cell Growth Without Conditioned Medium. C. Xu, E. Rosler, J. Jiang, J. Lebkowski, J. Gold, C. O’Sullivan, K. Delavan-Boorsma, M. Mok, A. Bronstein, M. Carpenter. Stem Cells 2005; 23: 315-323.

Immortalized Fibroblast-Like Cells Derived from Human Embryonic Stem Cells Support Undifferentiated Cell Growth. C. Xu, J. Jiang, V. Sottile, J. McWhir, J. Lebkowski, M. Carpenter. Stem Cells 2004; 22: 972-980.

Feeder-free growth of undifferentiated human embryonic stem cells. C. Xu, M. Inokuma, J. Denham, K. Golds, P. Kundu, J. Gold, M. Carpenter. Nature Biotechnology 2001; 19: 971-974.

Synthetic peptide-acrylate surfaces for long-term self-renewal and cardiomyocyte differentiation of human embryonic stem cells. Z. Melkoumian, J. Weber, D. Weber, A. Fadeev, Y. Zhou, P. Dolley-Sonneville, J. Yang, L. Qiu, C. Priest, C. Shogbon, A. Martin, J. Nelson, P. West, J. Beltzer, S. Pal, R. Brandenberger. Nature Biotechnology 2010; 28(6): 606-612.

AST-OPC1
Preclinical Safety of Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitors Supporting Clinical Trials In Spinal Cord Injury. Catherine A. Priest, Nathan C. Manley, Jerrod Denham, Edward D. Wirth, III, Jane S. Lebkowski. Regenerative Medicine. Posted online on 8 Sep 2015.

Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cell Transplants Improve Recovery After Cervical Spinal Cord Injury. J. Sharp, J. Frame, M. Siegenthaler, G. Nistor, H. Kierstead. Stem Cells 2010; 28:152-163.

Immunological properties of human embryonic stem cell-derived oligodendrocyte progenitor cells. R. Okamura, J. Lebkowski, M. Au, C. Priest, J. Denham, A. Majumdar. Journal of Neuroimmunology 2007; 192: 134-144.

Oligodendrocyte Progenitor Cells Derived from Human Embryonic Stem Cells Express Neurotrophic Factors. Y. Zhang, J. Denham, S. Thies. Stem Cells and Development 2006; 15: 943-952.

Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cell Transplants Remyelinate and Restore Locomotion After Spinal Cord Injury. H. Kierstead, G. Nistor, G. Bernal, M. Totoiu, F. Cloutier, K. Sharp, O. Steward. Journal of Neuroscience 2005; 25: 4694-4705.

Human Embryonic Stem Cells Differentiate into Oligodendrocytes in High Purity and Myelinate After Spinal Cord Transplantation. G. Nistor, M. Totoiu, N. Haque, M. Carpenter, H. Kierstead. GLIA 2005; 49: 385-396.

AST-VAC1 & AST-VAC2
Dendritic cells reconstituted with human telomerase gene induce potent cytotoxic T-cell response against different types of tumors. M. Frolkis, M. Fischer, Z. Wang, J. Lebkowski, C. Chiu, A. Majumdar. Cancer Gene Therapy 2003; 10: 239-249.

Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells. S. Nair, A. Heiser, D. Boczkowski, A. Majumdar. M. Naoe, J. Lebkowski, J. Vieweg, E. Gilboa. Nature Medicine 2000; 6: 1011-1017.

Telomerase mRNA-Transfected Dendritic Cells Stimulate Antigen-Specific CD8+ T Cell Responses in Patients with Metastatic Prostate Cancer. Z. Su, J. Dannull, B. Yang, P. Dahm, D. Coleman, D. Yancey, S. Sichi, D. Niedzwiecki, D. Boczkowski, E. Gilboa, J. Vieweg. Journal of Immunology 2005; 174: 3798-3807.

Modification of human embryonic stem cell-derived dendritic cells with mRNA for efficient antigen presentation and enhanced potency. K. Nishimoto, S. Tseng, J. Lebkowski, A. Reddy. Regen Med 2011; 6: 303-318.

Generation of immunogenic dendritic cells from human embryonic stem cells without serum and feeder cells. S. Tseng, K. Nishimoto, K. Silk, A. Majumdar, G. Dawes, H. Waldmann, P. Fairchild, J. Lebkowski, A. Reddy. Regen Med 2009; 4: 513-526.

Other Cell Types
Formation of Human Myocardium in the Rat Heart from Human Embryonic Stem Cells. M. Laflamme, J. Gold, C. Xu, M. Hassanipour, E. Rosler, S. Police, V. Muskheli, C, Murry. American Journal of Pathology 2005; 167: 663-671.

Human Embryonic Stem Cell-Derived Cardiomyocytes Can Be Maintained in Defined Medium Without Serum. C. Xu, J. He, T. Kamp, S. Police, X. Hao, C. O’Sullivan, M. Carpenter, J. Lebkowski, J. Gold. Stem Cells and Development 2006; 15: 931-941.

Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat heart. M. Laflamme, K. Chen, A. Naumova, V. Muskheli, J. Fugate, S. Dupras, H. Reinecke, C. Xu, M. Hassanipour, S. Police, C. O’Sullivan, L. Collins, Y. Chen, E. Minami, E. Gill, S. Ueno, C. Yuan, J. Gold, C. Murry. Nature Biotechnology 2007; 25: 1015-1024.

Human embryonic stem cell-derived cardiomyocytes engraft but do not alter cardiac remodeling after chronic infarction in rats. S. Fernandes, A. Naumova, W. Zhu, M. Laflamme, J. Gold, C. Murry. J of Molecular and Cellular Cardiology 2010; 49: 941-949.

hESC-Derived Cardiomyocytes Electrically Couple and Suppress Arrhythmias in Injured Hearts. Y. Shiba, S. Fernandes, W. Zhu, D. Filice, V. Muskheli, J. Kim, N. Palpant, J. Gantz, K. Moyes, H. Reinecke, B. VanBiber, T. Dardas, J. Mignone. A. Izama, R. Hanna, M. Viswanathan, J. Gold, M. Kotlikoff, N. Sarvazyan, M. Kay, C. Murry, M. Laflamme. Nature 2010; 489: 322-325.

Characterization and Enrichment of Cardiomyocytes Derived From Human Embryonic Stem Cells. C. Xu, S. Police, N. Rao, M. Carpenter. Circulation Research 2002; 91: 501-508.

Efficient generation and cryopreservation of cardiomyocytes derived from human embryonic stem cells. C. Xu, S. Police, M. Hassanipour, Y. Li, Y. Chen, C. Priest, C. O’Sullivan, M. Laflamme, W. Zhu, B. VanBiber, L. Hegerova, J. Yang, K. Delavan-Boorsma, A. Davies, J. Lebkowski, J. Gold. Regen Med 2011; 6(1): 53-66.

Neuregulin/ErbB Signaling Regulates Cardiac Subtype Specification in Differentiating Human Embryonic Stem Cells. W. Zhu, Y. Xie, K. Moyes, J. Gold, B. Askari, M. Laflamme. Circulation Research 2010; 107: 776-786.

Generation of Insulin-Producing Islet-Like Clusters from Human Embryonic Stem Cells. J. Jiang, M. Au, K. Lu, A. Eshpeter, G. Korbutt, G. Fisk, A. Majumdar. Stem Cells 2007; 25: 1940-1953.